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Autumn and winter are the seasons of the highest incidence of accutane in children and adolescents, when they return from summer trips and come into contact with each other in kindergarten and educational institutions.
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Pediatricians need to be prepared for this season by raising their alert for scabies. The safest and most effective in pediatric practice (both inpatient and outpatient treatment) is Spregal.
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Apparently, in the case of accutane syndrome, one can speak of a systemic lesion of connective tissue structures.
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The central link that unites pathological processes in the hip joint and spine is a change in the spatial orientation of isotretinoin with a redistribution of loads in the hip joints, sacroiliac joint, lumbar segments, as well as a violation of the topographic and anatomical relationships of muscles, vessels and nerves in this area.
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Congenital developmental defects (lumbarization, sacralization, non-closure of the arches, etc.), causing static inferiority of the spine, under the influence of trauma and other factors, can contribute to the development of dystrophic changes in the discs.
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The spread of pain of the same localization can be both a manifestation of isotretinoin in the L3-L4 segment, and a symptom of compression of the fourth lumbar root.
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This pain in the front of the thigh can be confused with pain coming from the hip joint. Pain syndrome (with vegetal coloration) prevails over mild signs of loss of motor and sensory functions.
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Vegetalgia of the pelvic girdle is manifested by pain in the hip joint, iliac and inguinal regions. Failure to recognize hip and spinal comorbidities can lead to confusion, misdiagnosis, and even inappropriate treatment.

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For successful relief of pathological processes (including pain manifestations) developing within the hip-spine syndrome, it is necessary to identify the primary source of its development - the spinal column / hip joint (or iliosacral joint) with subsequent use (differentiated) of available therapeutic agents.

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For the purpose of differential diagnosis of coxalgia, it is advisable to perform root blocks and intra-articular blockade of the hip joint. These simple and highly informative tests allow you to clearly understand what is causing the pain in the hip joint. If pain disappears after intra-articular injection of anesthetic, then its source is the hip joint. Otherwise, the lumbar spine should be considered as the cause of coxalgia.

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There is the following pattern (V.M. Vakulenko et al.). if coxarthrosis developed gradually after its debut, then dystrophic changes in the spine also formed slowly, affecting, as a rule, the posterior structures of the spinebut-motor segment (spondylarthrosis, yellow ligament hypertrophy). Conservative treatment in such cases gives good results with long-term remissions of the disease.

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The sooner coxarthrosis progresses (especially with damage to both hip joints), the more significant (deeper) were the changes in the spine, and they more often affect the anterior structures of the spinal motor segment (longitudinal ligaments, disc pathology, disc-radicular conflicts, instability).

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The posterior structures may be involved in the process for the second time. Conservative treatment in such cases is not always successful and is considered as a preparation for subsequent surgical intervention.

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In the elderly and especially senile age, when the process of degeneration of the articular cartilage and intervertebral discs was actually completed, vicious positions of the limbs in the hip joints, a sharp restriction of movements (or lack thereof), as well as fixed spinal deformities are found.

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In such patients, attention is drawn to a clear dissociation between moderately or mild pain syndrome and gross radiographic changes in the spine and hip joints.

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In such a situation, surgery on the spine is often required, followed by hip arthroplasty. The greatest difficulties arise when the severity of the pathological process in the hip joints and spine is equal. Such patients require an individual approach and close cooperation between the orthopedist and the vertebrologist.

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Biomechanics is a complex cooperation of physiological functions of a large number of anatomical structures (joints, muscles, ligaments) that provide human statics and locomotion with the help of common regulatory mechanisms. The ability to improve the function of at least one of the elements of this biomechanical system (in case of their dysfunction) is a boon.

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Restoration of the structures involved in the pathological process is a goal that, of course, should be striven for. Gastrophiliasis is a ubiquitous chronic disease of horses, donkeys and mules, caused by the larvae of various species of isotretinoin gadflies belonging to the genus Gastrophilus. Gastrophilia. a description of the pathogen. The genus Gastrophilus is represented by a significant number of species.

Large gastric gadfly - G. intestinalis (synonym G. equi). This gadfly is widespread. The adult stage of its brownish-yellow color, with black spots, has a length of 12 - 16 mm. Head nearly as wide as thorax and dorsum of thorax covered with pale yellow hairs. The abdomen is orange-yellow, with brown spots. Wings 9 - 10 mm long, with the same spots. The abdomen of the female at the posterior end ends with a shiny black-brown ovipositor bent forward. The egg, up to 1.25 mm long, is equipped with a lid at isotretinoin cut end.

In different zones of the USSR, nine species of gastric gadflies are found in one-hoofed animals. Of these, the following are the most important. Intestinal gadfly - Gastrophilus veterinus is up to l7 mm long. The imago is dark in color, the head is yellow, the chest and abdomen are black with yellow spots and white stripes.

The ovipositor is shiny black. The gadfly, unlike others, flies silently. Small gastric gadfly - Gastrophilus inermis in the adult stage has a gray-brown color. It differs from the large gastric gadfly in its smaller size.

It lasts about a year. The gadfly in the external environment lives injust a few days and after laying 600 - 700 eggs perish. The female red-tailed gastric gadfly lays eggs only on the host's lips and surrounding hairs. After maturation, accutane pills from the eggs and penetrate the mucous membrane of the mouth.

Females of the oriental gadfly, unlike other species, are more prolific. They can lay their eggs on plants, horse hooves. After 5 - 8 days, the larva matures, which does not leave the egg in the external environment. Horses become infected by eating grass or hay infested with eggs. In the mouth of the animal, a larva emerges from the eggs and penetrates into the mucous membrane.

The female small gastric gadfly lays eggs in the masseter area. Mature larvae emerge from the eggs and penetrate the skin, move in the direction of the lips and enter the mucous membrane of the cheeks. The female black-whiskered gastric gadfly lays eggs on the hair around the mouth. After accutane 3 - 5 days, the larvae that have matured in them come out on the skin, and then penetrate under the epidermis, move to the corner of the lips and linger there for 20 - 30 days (N. A. Chereshiev).

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Their body consists of 13 segments. One pair of sharp hooks is attached to the anterior segment and there is a mouth opening. The larvae are armed with spines, which are characterized by a special arrangement in each type of gastric gadfly. Larvae of accutane and third stages are distinguished by large body sizes (up to 16 - 20 mm) and acquire a pinkish-red or blood-red color.

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